Low levels of pancreatic elastase 1 in stools of preterm infants.

Faecal elastase 1 levels in premature and full term infants.

BACKGROUND Determination of faecal elastase 1 (FE1) is a simple, relatively inexpensive, non-invasive, highly specific and sensitive test for determining pancreatic function. Secretion of pancreatic enzymes varies during infancy, but there are almost no specific data on the ontogeny of elastase 1 in human babies. AIM To study FE1 levels in preterm and term babies, and to determine the possibl...

Relationship of proteinases and proteinase inhibitors with microbial presence in chronic lung disease of prematurity

BACKGROUND A proteolytic imbalance has been implicated in the development of "classical" chronic lung disease of prematurity (CLD). However, in "new" CLD this pattern has changed. This study examines the longitudinal relationship between neutrophil proteinases and their inhibitors in ventilated preterm infants and their relationship to microbial colonisation. METHODS Serial bronchoalveolar la...

Fecal Elastase-1 Levels in Preterm Infants with Bronchopulmonary Dysplasia

مقایسه تست های تشخیصی الاستاز 1 مدفوعی و تریپسین مدفوع در بیماران فیبروز کیستیک با گروه شاهد

Background & Aims: Pancreatic Elastase–1 (EL-1) is a human specific protease enzyme, produced and secreted by pancreatic acinar cells. This enzyme is stable and is not affected by prescriptions of supplement pancreatic enzymes, and it has good connection with pancreatic stimulation function tests. The Purpose of this study is to compare fecal pancreatic elastase–1 concentration in patients wi...

Inflammatory bronchopulmonary response of preterm infants with microbial colonisation of the airways at birth.

The inflammatory indicators in the tracheobronchial aspirate (TA) of 81 ventilated preterm infants with microbial colonisation of the airways and in non-colonised neonates were analysed on the first day of life. TA was assessed for chemotactic activity, neutrophil cell count, and concentrations of leukotriene B4, C5a, interleukin-1, interleukin-8, elastase-alpha 1-proteinase inhibitor, free ela...